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2021 ACR/VF Guidelines for Management of Eosinophilic Granulomatosis with Polyangiitis (EGPA)

#EGPA #Eosinophilic #Granulomatosis #Polyangiitis #ACR2021 #Management
2021 ACR/VF Guidelines ... for Management ... of Eosinophilic ... #rheumatology # ... algorithm #vasculitis
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management
 • Giant Cell Arteritis (GCA)
 •
Vasculitis Management ... - ACR/VF 2021 Guidelines ... Polyangiitis (MPA) • Eosinophilic ... @MithuRheum #Vasculitis ... Guidelines #algorithm #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Active
Eosinophilic Granulomatosis ... (EGPA) - ANCA Vasculitis ... Management Algorithm ... - ACR/VF 2021 Guidelines ... Guidelines #algorithm #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
) • Systemic lupus ... scleroderma) - Anti-Scl ... ANCA-Associated Vasculitis ... ANCA+ 60% • Eosinophilic ... antibodies #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• EGPA: - Eosinophilia ... inflammation Others: • Lupus ... such as systemic lupus ... retinopathy Lab Tests ... differential #diagnosis #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
specific laboratory tests ... phase reactants, eosinophilia ... No necrosis, No vasculitis ... Disease #diagnosis #management ... workup #treatment #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Evans • ITP • Cl-NH ... to cold IgG • Lupus ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology