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diagnosis management differential acidosis amiodarone anthracycline antidote cardiology cardiotoxicity chemotherapy classification clozapine criticalcare crystalloids diuresis diuretics elevation encephalopathy excretion foamed
REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia
99: Serotonin Syndrome ... Hyperthermia (most common cause ... Cornerstone of treatment ... discontinuing all ... SerotoninSyndrome #management #toxicology
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... Clozapine is known to cause ... #Toxicity #Diagnosis ... #Pharmacology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
(PRES) Overview ... Medication/Drug toxicity ... the underlying cause ... • Treatment of ... with AEDs until cause
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... respiratory distress syndrome ... Exclude other causes ... macrophages Treatment ... diagnosis #management #Toxicology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
/ hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome ... lactate and can act
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome ... Inhibitors of Na+K+2Cl ... Kidney stones caused ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology
The crusade against “Ab”Normal Saline continues. This is a non-physiologic fluid that can harm our
this post will focus ... its Chloride (Cl ... K+ in the ECF causes ... management #diagnosis #treatment ... #pharmacology #
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... - Overview of IRIS ... unintentional weight loss, nausea ... Drug reaction/ART toxicity ... #Inflammatory #Syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Overview Epidemiology ... Hypocomplementemia • Can cause ... Adenocarcinoma Treatment ... lubricants • Pharmacologic
Methotrexate Toxicology Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... (folinic acid) treatment ... be effective in all ... #Toxicity #Management ... #Pharmacology
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