28 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Algorithm and Causes ... Hemolysis #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Hemolytic anemia ... - Anti-B2GP1 (aPL ... ) 30-45% Differential ... symptoms #mimickers #differential ... #rheumatology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... failure - CAD/ACS ... Transverse myelitis • Hematology ... : - Anemia • ... #dyspnea #sob #differential
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... comparison #table #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... #differential # ... diagnosis #hematology ... #anemia
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... the face (many differential ... search ANA and aPL ... including in children (pediatric ... erythematosus #rheumatology
Great Mimickers - SHALLOTS Mnemonic

S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
dermatitis, dementia, anemia ... anything L - Lupus ... Could be lupus in ... fatigue, and oh yeah all ... Mnemonic #Diagnosis #Differential
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Alzheimer - 1st cause ... - Progressive amnesia ... Dementia - 2nd cause ... MNCD #Dementia #Differential ... #Diagnosis #Geriatrics
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Diffuse and Focal) Differential ... Irreversible-biopsy required • Lupus ... • Discoid lupus ... #Differential # ... Diagnosis #Algorithm #causes