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hepatology differential liver causes lfts management transaminitis chronic aclf aih cardiology chemistry cirrhosis coagulation comparison deficiencies deficiency dermatology dili druginduced
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... #algorithm #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... Drug-Induced liver injury ... - Autoimmune ... #Differential #Hepatology ... #Diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Failure Infections Alcohol-Associated ... Drug-Induced Liver Injury ... gastroenterology #management #diagnosis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... > 20x normal - Acute ... Patterns #Liver #Injury ... #hepatology #LFTs ... #differential #diagnosis
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
- Differential Diagnosis ... Algorithm Malignant ... Inflammatory • Alcoholic ... Hepatitis • Autoimmune ... #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute ... steatosis • Autoimmune ... #Diagnosis #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
- Differential Diagnosis ... Algorithm Severe ... • Ischemia • Autoimmune ... • NAFLD • Alcohol ... hepatitis • Drugs
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... Drugs (MDMA), Alcohol ... Other: NAFLD, Autoimmune ... #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular ... : Autoimmune hepatitis ... ALT Ratios: • Alcoholic ... #diagnosis #algorithm
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Liver Disease - Alcohol ... , Viral hepatitis ... , Autoimmune • ... table #comparison #diagnosis ... #hematology #deficiency
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