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hepatology liver differential management causes lfts transaminitis aclf aih chemistry chronic cirrhosis comparison deficiencies deficiency dermatology dili druginduced failure gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Kidney Failure Coagulation ... Failure Infections Alcohol-Associated ... Drug-Induced Liver Injury ... gastroenterology #management #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... #algorithm #hepatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... Liver Disease - Alcohol ... , Viral hepatitis ... table #comparison #diagnosis ... #hematology #deficiency
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute ... steatosis • Autoimmune ... #Diagnosis #Algorithm
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... Drugs (MDMA), Alcohol ... Other: NAFLD, Autoimmune ... #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular ... : Autoimmune hepatitis ... ALT Ratios: • Alcoholic ... #diagnosis #algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... • Albumin • Coagulation ... ALT Ratios: • Alcoholic ... liver #chemistry #diagnosis ... #differential #Hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... subclinical disease to acute ... pattern of liver injury ... regarding need for treatment ... #Hepatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... Palpable Rash: - Autoimmune ... Complete blood count coagulation ... • Serology for hepatitis
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... : - Acute kidney ... injury with serum ... #Algorithm #hepatology
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