11 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Tablets - Estimated A1c ... Metformin + DPP4 ... dapagliflozin) Dpp4 ... Tablets #Oral #DM2 #Pharmacology ... #Pills #Endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... Action: Inhibits DPP ... #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... linagliptin) 5 mg DPP4 ... has a smaller A1c ... Renal #Dosing #Pharmacology ... Diabetes #DM2 #Endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
summarizes the A1C ... #pharmacology #pharmacotherapy ... medications #diabetes #endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... #Medications #pharmacology ... comparison #table #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... Diabetes #DM2 #Endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
Patients without clear ... Weight #Based #pharmacology ... #endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
have significant A1c ... empagliflozin and DPP4 ... semaglutide #Diabetes #Pharmacology ... #Endocrinology
Huge mural thrombus occupying 1/3 the LV.
MI effecting [LAD territory]

In PLAX view, The unechoic line between
Huge mural thrombus ... the clot is very clear ... EchoAshwag #Mural #Thrombus ... echocardiogram #pocus #a4c