21 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... Relevant HES Variants ... #HES #Hematology ... #eosinophilia # ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... and Management ... than 1500 and clinical ... #HES #eosinophilia ... #diagnosis #hematology
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Eosinophilic Gastroenteritis ... Severity of the Disease ... + Concern for HES ... : • Hematology ... Gastroenteritis #Treatment #management
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- MAHA: TTP, HUS ... Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... Laboratory Tests ... Differential #Diagnosis #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... is a skin prick test ... #diagnosis #management ... signs #symptoms #rheumatology
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
cephalosporin by Test ... carbapenems by Test ... nephritis, Drug rash eosinophilia ... there is a strong clinical ... Prescription #algorithm #management
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Clinical history ... specific laboratory tests ... phase reactants, eosinophilia ... #diagnosis #management ... workup #treatment #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology