9 results
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
rubbing of the skin ... differentiating between the diagnosis ... #TEN #Dermatology ... #PhysicalExam # ... Clinical #SJS #skin
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
organ-specific signs ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
- Differential Diagnosis ... migrans: • Target sign ... gabrieltalledop #dermatology ... #differential #diagnosis ... #peds #pediatrics
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... Inverse Gottron’s sign ... ulcerations • Skin ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... Lymphocytic #Leukemia #diagnosis ... workup #oncology #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign")

Asboe-Hansen sign is the extension
clinical tool for diagnosing ... bulla for lesional skin ... #PhysicalExam # ... Bullae #Blister #Dermatology ... #skin
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... Dermatomyositis #diagnosis ... #management #rheumatology ... #dermatology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
membrane bleeding and skin ... Disorders #History #peds ... #pediatrics #diagnosis ... #hematology #primarycare