9 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Drug-induced Liver Injury ... dose dependent injury ... induced #Liver #Injury ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... Diagnosis Algorithm ... involvement, Kidney injury ... #Diagnosis #Algorithm ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... vein: Budd-chiari syndrome ... • Iatrogenic: DILI ... • Gilbert's syndrome ... #hepatology
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Differential Diagnosis Algorithm ... • Nephrotic syndrome ... • Postcardiac injury ... Pulmonary #Diagnosis #Algorithm ... #Hepatology #causes
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
Non-accidental Injury ... neurology, back pain Haematology ... cell disease Rheumatology ... #Limping #NWB #Algorithm ... Pathway #Child #Peds
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... obstruction, HELLP Syndrome ... Sophia_Hayes_MD #Liver #Injury ... Causes #Acute #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
ALF): • Liver injury ... Unconjugated Bili ... > 90% of Total Bili ... • Gilbert's syndrome ... #differential #Hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Hepatitis - Management Algorithm ... - Acute kidney injury ... HCV, DILI, HCC, ... Hepatitis #Management #Algorithm ... #hepatology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
non-accidental injury ... Marfan syndrome, ... Disorders #History #peds ... pediatrics #diagnosis #hematology