14 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulant Sites of Action ... #Medications #Pharmacology ... #Pathophysiology ... #Mechanisms #DOAC
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... , Intermediate Action ... Blockade, Fast Action ... Antiarrhythmics #Pharmacology ... #pathophysiology
Class I Antiarrhythmics and their Key Pharmacologic Properties

Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer")
Class IB
and their Key Pharmacologic ... depolarization (phase ... This type of action ... channels involved in phase ... #Pharmacology #
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
, Intermediate Action ... Blockade, Fast Action ... Blockade, Slow Action ... Vaughan #Williams #Pharmacology ... #pathophysiology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... binding to its active ... #Pharmacology #Pathophysiology ... Heparins #LMWH #UFH #DOAC ... #Fondaparinux #NOAC
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... rate (lengthens phase ... 4 and phase O of ... #Pathophysiology
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
macrophages, HLA class ... Phase -> (initiated ... Phase (occurs 4 ... phase) Presence ... Rhinitis #Rhinorrhea #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
organic acids and bases ... Henle's loop (TAL) - Active ... tubule (DCT) - Active ... Segments #Function #Pathophysiology ... Tubules #Table #Pharmacology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... signs/symptoms of active ... decreased reflexes Pathophysiology ... - Continuation phase
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
Follicular phase ... granulosa cells (activin ... Secretory phase ... , progesterone causes ... #OvarianCycle #pathophysiology