16 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Pathogenesis and clinical ... leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... Complications: • Acute Asthma
Assessment of the Child with Chronic Asthma
Are there other allergic disorders?
 - Allergic rhinitis
 - Eczema,
Asthma Are there ... other allergic ... - Allergic rhinitis ... triggers: - Allergic ... #diagnosis #peds
Allergic Rhinitis
Mild to severe persistent nasal mucosal inflammation to specific allergic triggers
WHO? 
 • 1 in
Allergic Rhinitis ... inflammation to specific allergic ... Associations: • Asthma ... Sinusitis • Allergic ... NUIM_Chiefs #Allergic
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Glucocorticoids Pugs (Allergies ... ): - Allergic ... Rhinitis - Allergic ... Dermatitis - Asthma ... Hypereosinophilic Syndrome - Chronic
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
cough, SOB • Chronic ... 45yo, F; Hx of asthma ... /allergies; Cough ... loss, malaise • Allergic ... Weeks) - Hx of asthma
On the left we see a chest film with a typical finger-in-glove shadow.
The HRCT shows focal
the appropriate clinical ... setting (asthma ... eosinophilia) typical for Allergic ... #Clinical #Radiology ... CTChest #ABPA #Allergic
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
histiocytosis • Allergic ... : Asthma, Eczema ... insufficiency, Chronic ... Diagnosis #Algorithm #allergy
Cough - Diagnostic Schema

Infectious: URTI, LRTI, Bacterial, Viral
Irritant/Exposure: Allergic, Post-infectious, Pneumonitis, ACEi, PTX, Foreign Body
Airway Disease:
Irritant/Exposure: Allergic ... Airway Disease: Asthma ... Schema #Acute #Chronic
The infant with tachypnea or wheeze - Clinical Conditions to Consider
 - Bronchiolitis 
 - Pneumonia
tachypnea or wheeze - Clinical ... infection - Atopic asthma ... family history of allergy ... #Diagnosis #Peds
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
released during an allergic ... reaction or asthma ... Disorders: • Chronic ... ’s Disease • Asthma