25 results
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
clinically) and asthma ... /eosinophils No ... Inflammation: • No Asthma ... (GPA) • Both asthma ... ANCA #Vasculitis #differential
Eosinophilic Pneumonia
When to suspect Eosinophilic Pneumonia? Non-resolving pneumonia + BAL > 25% eosinophils + excluded more
Eosinophilic Pneumonia ... Effusions - Rare Peripheral ... tobacco hx, >60% asthma ... Constitutional Symptoms - Peripheral ... edema" - Common Peripheral
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
asthma • Mepolizumab ... q4 weeks • Peripheral ... q4 weeks • Peripheral ... q8 weeks • Peripheral ... #asthma #Biologic
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
therapies for Asthma ... , and ACO initially ... analysis with eosinophil ... summary of the differential ... ACO = asthma-COPD
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... FOR TESTING: • Peripheral ... blood eosinophilia ... common causes are asthma ... Disorders #Algorithm #Differential
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Eosinophilia - Differential ... Primary Eosinophilia ... Secondary Eosinophilia ... histiocytosis • Allergic: Asthma ... #Differential #
Pediatric Dyspnea - Differential Diagnosis Algorithm
Stridor:
 • Croup
 • Foreign Body
 • Tracheitis
 • Epiglottitis
 •
Laryngospasm Wheeze ... : • Asthma • ... Viral Induced Wheeze ... Pneumonia • Asthma ... Algorithm #Causes #Peds
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Approach to Eosinophilic ... Diseases • Acute Eosinophilic ... 45yo, F; Hx of asthma ... Weeks) - Hx of asthma ... Diseases #pulmonary #differential
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential ... DRESS - AIN - Eosinophilic ... Dermatitis - Asthma ... #Differential #
Causes of Pediatric Wheezing - Differential Diagnosis Algorithm
CXR Abnormal:
 • Pulmonary Sequestration
 • Congenital Adenoid Cystic
Pediatric Wheezing - Differential ... Beta-Agonist: • Asthma ... Cystic Fibrosis Wheeze ... #Differential # ... Algorithm #Causes #Peds