11 results
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
asthma • Mepolizumab ... q4 weeks • Peripheral ... #asthma #Biologic ... #pharmacology #pulmonary ... #management
Eosinophilic Pneumonia
When to suspect Eosinophilic Pneumonia? Non-resolving pneumonia + BAL > 25% eosinophils + excluded more
Effusions - Rare Peripheral ... tobacco hx, >60% asthma ... Consolidations AKA "inverse pulmonary ... edema" - Common Peripheral ... Pneumonia #diagnosis #pulmonary
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
45yo, F; Hx of asthma ... SOB, sinusitis, wheezing ... Weeks) - Hx of asthma ... food hx; Fever, wheezing ... Lung #Diseases #pulmonary
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
therapies for Asthma ... , and ACO initially ... analysis with eosinophil ... ACO = asthma-COPD ... #Diagnosis #Management
Severe Asthma Exacerbation
Signs of a Severe Asthma Exacerbation:
 • Vitals: ↑HR ↑RR ↓SpO2
 • High work
Severe Asthma Exacerbation ... Signs of a Severe Asthma ... sentences • Diffuse wheezing ... #CriticalCare #pulmonary ... ventilation #mechanical #management
Causes of Pediatric Wheezing - Differential Diagnosis Algorithm
CXR Abnormal:
 • Pulmonary Sequestration
 • Congenital Adenoid Cystic
Causes of Pediatric Wheezing ... Abnormal: • Pulmonary ... Beta-Agonist: • Asthma ... Algorithm #Causes #Peds ... #Pediatrics #Pulmonary
Asthma management- what is the evidence? 

MDI vs. Nebulization of Beta agonist 
 - Has been
Asthma management ... #asthma #management ... #ebm #pulmonary ... #peds #pediatrics
Allergic Bronchopulmonary Aspergillosis (ABPA)
WHAT IS IT?
Hypersensitivity response to Aspergillus fumigatus in the airways
 • Primarily affects
with underlying asthma ... • Wheezing • Increased ... Aspergillus • Peripheral ... eosinophilia and ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), EGPA (eosinophilic ... (DAH), asthma in ... nodules, asthma ... sparing of the lung periphery ... differential #diagnosis #management
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
hoarseness, and wheezing ... Laryngeal and pulmonary ... Laryngitis • Asthma ... Disease #diagnosis #management