12 results
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
(APS) APS is a ... Anticardiolipin antibodies (aCL ... 1 of the three aPLs ... to be present Treatment ... #management #anticoagulation
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... have fever - ACS ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS
Venous Thrombosis - Arterial Thrombosis
INR Target
Duration
Recurrence

Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... ) APS Venous Thrombosis ... #APS #management ... #rheumatology #hematology ... #treatment
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... presentation of ALS ... (1) limb-onset ALS ... ) bulbar-onset ALS
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... unless severe APLS ... coagulopathy, RRT/IMV as ... APML #diagnosis #management
HEART Score – A Tool For the ED The HEART score is an excellent tool that
Acute Coronary Syndrome ... (ACS) for admission ... further workup and treatment ... well as high risk ... #Diagnosis #Management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... Generalized fatigue - ALS ... Diagnosis - Clinical ... Clinical DX: - ... Gravis #diagnosis #management
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
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Anti-Smooth Muscle Abs ... Anti-LKM & Anti-ALC Abs ... regarding need for treatment ... AIH #Diagnosis #Management ... #Hepatology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
dependent DM ACS ... Change in clinical ... risk (>5%): - Aortic ... • <12mo since ACS ... medical and surgical management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... (for secondary APS ... cerebritis #diagnosis #management ... #treatment