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diagnosis differential algorithm causes management clinical nephrology pharmacology pathophysiology endocrinology treatment cardiology secondary table hematology hepatology comparison workup neurology radiology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
(ALT or AST > ALP ... Wilsons, Pregnancy - AFLP ... Cholestatic Pattern (ALP
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... Diagnosis Algorithm ALP ... - Increased ALP ... - Drugs - Primary ... #Phosphatase #ALP
Primary sclerosing cholangitis (PSC) - Malignancy Screening and Surveillance Recommendations Cholangiocarcinoma - Annual US or
Primary sclerosing ... q 6 months +/- AFP ... GregoryTBrennan #Primary
Hypophosphatemia - Measurement of urine phosphate excretion - Differential Diagnosis Algorithm • GI loss • Redistribution
Redistribution • Primary ... deficiency • Primary ... Hypophosphatemia #urine #urinary
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
ALP enzyme- Discovered ... in 1923 Low ALP ... 1948 by Rathbun ALP ... , ↓ALP → Low ... • Elevation of urinary
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
of Pregnancy (AFLP ... TTPHUS #HELLP #AFLP
Causes of AKI in Pregnancy - Differential Diagnosis Creatinine - Platelets - Transaminases - LDH - PT/PTT
Nephritis • AFLP
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Elevated ALP 2. ... with PBC #PBC #Primary
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
(Alk phos/ULN ALP ... • AST/ALT > ALP ... Cholestasis • ALP ... disease • If ALP ... • Elevation of ALP
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
for the liver ALP ... Transaminase, ALP ... / ULN ALT) / (ALP ... / ULN ALP)
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