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diagnosis differential algorithm causes chronic cll lymphocytic classification comparison disorders focal hemeonc hodgkins localized lymphoma lymphomas lymphoproliferative management mds myelodysplasia
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... • Neoplastic (Leukemia ... #LAD #Differential ... Algorithm #Causes #Hematology ... #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphadenopathy ... #LAD #Differential ... Algorithm #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
of ALL is of B-cell ... pain • Bulky lymphadenopathy ... involvement • T-cell ... activity • ↓ LAP ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... early symptoms • Lymphadenopathy ... Exam/Signs: • Lymphadenopathy ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Most common leukemia ... ) Asymptomatic lymphadenopathy ... Transformation to large cell ... Symptomatic massive lymphadenopathy ... #oncology #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
(NHL) ~60% - lymphadenopathy ... more diffuse, can ... ~10% - B-Cell ... Treated Like Acute Leukemias ... pathophysiology #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involved) • No leukemic ... disease: B symptoms, lymphadenopathy ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... compounds, alcohol, lead ... Syndromes #diagnosis #hematology ... #oncology
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