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diagnosis hematology differential management blood dermatology hit induced product reactions 4ts 4tscore acronym bleeding bruising coagulation dic disseminated intravascular likelihood
Approach to suspected Heparin-Induced Thrombocytopenia (HIT) • Suspected HIT Algorithm • "4 T's" clinical probability score:
Suspected HIT Algorithm ... (platelet count ... Timing of onset of platelet ... NephPrasad #Heparin ... #HIT #hematology
PLATELETS Mnemonic for Causes of Thrombocytopenia P - Platelet Disorders (DIC, ITP, TTP) L - Leukemia, Lymphoma A -
PLATELETS Mnemonic ... for Causes of Thrombocytopenia ... P - Platelet ... Toxin (Drug or Heparin-induced ... S - Sepsis #PLATELETS
4-T Score for the Likelihood of Heparin Induced Thrombocytopenia - Thrombocytopenia - Compare the highest platelet count
Likelihood of Heparin ... Compare the highest platelet ... - Timing (of platelet ... Other potential cause ... #4TScore #HIT #Heparin
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
RBC's secondary to platelet ... inflammation • Thrombocytopenia ... • Platelet defects ... : Platelet Defects ... : - Thrombocytopenia
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... Findings in DIC: • Platelet ... - Platelet rich ... Treat primary cause
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Thrombocytopenia ... Sequestration Disordered Platelet ... #Causes #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... hemostasis: - Thrombocytopenia ... - Abnormal platelet ... Henoch Schonlein Purpura
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... intravascular hemolysis Platelet ... and decreased platelet ... Diagnosis #Workup #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
donor (apheresis) platelets ... transfusion, due to anti-platelet ... Causes purpura & ... common following platelet ... contamination: Platelets
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
transfusion, due to anti-platelet ... Causes purpura & ... severe thrombocytopenia ... common following platelet ... contamination: Platelets
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