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diagnosis hematology differential management intravascular product reactions cirrhosis coagulation dermatology disseminated extravascular hemolysis hemolytic leukemia nonpalpable oncology palpable rheumatology thromboticthrombocytopenicpurpura
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... : - Thrombocytopenia ... - Hemolytic anemia ... Fulminans (DIC ... Differential #Diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... Treat primary cause ... Coagulation #diagnosis #causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation (DIC ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... #anemia
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... RETIC INDEX: • Blood ... splenomegaly, Thrombocytopenia ... Wilson's disease, DIC-low ... Differential #Diagnosis #Hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... result in severe anemia ... of Peripheral blood ... immune hemolytic anemia
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... Post Transfusion Purpura ... Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... Post Transfusion Purpura ... Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... , thrombocytopenia ... Fibrinolysis & DIC ... #Leukemia #Hematology
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