2 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... leukocytosis and coagulopathy ... PCC to reverse coagulopathy ... Differentiation #Syndrome #APML ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... protein C and S Pathophysiology ... or consumption coagulopathy ... #Coagulation #diagnosis ... treatment #management #hematology