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management rheumatology activation adult bleeding cardiology differential disease disorders endocarditis hemeonc hemophagocytic hepatology hepatorenal history hlh hrs infectiousdiseases lymphohistiocytosis macrophage
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE], AOSD ... Histopathologic criteria ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Treatment - Mild ... : NSAIDS Treatment ... Prednisone 0.5-1mg/kg ... Stills #disease #AOSD ... #diagnosis #rheumatology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Criteria): • ↑ ... Treatment Overview ... #Hepatorenal #Syndrome ... #Hepatology #Nephrology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... Treatment Approach ... #Management #Hematology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Drug history, e.g ... Marfan syndrome, ... Disorders #History #peds ... #pediatrics #diagnosis ... #hematology #primarycare
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Cholesterol emboli syndrome ... Paradoxical emboli via ASD ... → TEE • Duke Criteria ... ↑ ESR, CRP • EKG ... hematuria, + RF Treatment
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