9 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... ): - Hematologic ... Lower-extremity weakness, urinary ... sticky” cells; WBC ... #Emergencies #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
count ↑ PLT • ↑ PBS ... + distinctive primary ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... Cold Agglutinin Syndrome ... Blood smear - RBC ... younger pts) Differential ... hemolytic #anemia #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... platelets - WBC ... Immunohistochemical studies (to differentiate ... through Ann Arbor criteria ... #hematology #oncology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... presence of metabolic syndrome ... criteria should ... body mass index; FBC ... Liver #Enzymes #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... the context of primary ... vein thrombosis Hematologic ... Induced Lupus: • Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Presentation - Systemic Symptoms ... Lab Tests: • CBC ... #diagnosis #rheumatology ... #classification
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... • Primarily occurs ... Hematologic malignancy ... NTM #Infections #differential