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Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
Diagnosis and Management ... Summary Primary ... : Most Common Cause ... Insufficiency #Primary ... Secondary #Diagnosis #Management
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
diagnostic of primary ... OR secondary AI ... unclear (often the case ... suggests EITHER primary ... ACTH: - High = primary
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... aldosterone Causes ... : Most Common Causes ... AI present - ... AI present -
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary ... Pathophysiology Primary ... AI = adrenal glands ... Secondary AI = the ... Medicine @ucsdim #Primary
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
specificity for AI ... > 15 excludes AI ... Differentiate primary ... vs secondary AI ... consistent with primary
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Causes of Adrenal ... ACTH-Independent (Primary ... Insufficiency #AI ... Diagnosis #Algorithm #Causes
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... either secondary or primary ... Gitelman's syndrome • Primary ... diagnosis #algorithm #causes
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Common causes of ... OBSTRUCTIVE • Urinary ... Glomerulonephritides (GN) • Primary ... Disease process primarily ... NephroP #AKI #causes
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
Causes of Secondary ... Testing Common causes ... angiography • Primary ... repaired) • Primary ... syndromes other than primary
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
urinalysis, labs - Management ... renal biopsy - Management ... Obstruction to urinary ... prostate hypertrophy, urinary ... ultrasonography - Manaqement
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