570 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... Pharmacology #Causes #DILI
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... Injury (DILI) ... DILI Types: ... or symptoms of liver ... Drug #induced #Liver
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
The Liver Consult ... GTT, indirect bili ... MELD - Chronic liver ... disease work up - Liver ... US - Prior liver
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Causes of Acute Liver ... • Iatrogenic: DILI ... Unconjugated Bili ... > 90% of Total Bili
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... Alcohol-related liver ... cholangitis Consider liver ... #DrugInduced #Liver
Drug-Induced Liver Injury - Pathophysiology
Indirect
Idiosyncratic
Direct

BWH Medicine Chiefs @BrighamChiefs

#DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver ... BrighamChiefs #DILI ... #DrugInduced #Liver
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... of underlying liver ... disease, liver ... support, or liver ... Injury (DILI)
Amiodarone-Induced Lung Iniurv (AILI) - Timeline
Hours to days (peri-procedurally): ARDS
Days to months: DAH
Weeks: Eosinophilic pneumonia
Weeks to
Amiodarone-Induced Lung Iniurv (AILI ... Induced #LungIniurv #AILI
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Identify Acute Liver ... - Specific to liver ... Unconjugated Bili ... > 90% of Total Bili
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... specific for the liver ... abnormality vs bone Bili ... SinaiBmoreIMRes #Liver