20 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... Clinical TLS: • AKI ... other symptomatic hypocalcemia ... • Hypocalcemia ... TLS #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... Hyperphosphatemia • Hypocalcemia ... #causes #treatment ... #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... Pre-Renal: • Hypovolemia ... Distributive Shock, HRS, Hypercalcemia ... Abdominal Compartment Syndrome ... #causes #algorithm
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... or induced) #Hypokalemia ... #Causes #differential ... #diagnosis #nephrology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
heart failure, neurologic ... disorders including hypokalemia ... hormonal excess or hypokalaemia ... Vasculitis • Endocrinologic ... Neurologic disorders
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... hydration - Hyperkalemia ... TLS #diagnosis #management ... #hematology
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Congenital long QT Syndrome ... Hypomagnesemia • Hypokalemia ... • Hypocalcemia ... (rarely) Treatment ... 1b (lidocaine)- case
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... #management #pathophysiology ... #Hypokalemia
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Dermatomyositis) AKI ... - Pathophysiology ... Dialysis for severe hyperkalemia ... #Summary #causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #rheumatology # ... cerebritis #diagnosis #management