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Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Kidney Injury (AKI ... Framework PRE-Renal AKI ... INTRA-Renal AKI ... Immune-mediated, Infection-mediated ... POST-Renal AKI
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
disease - Post-infectious ... prolonged prerenal AKI ... Urinary tract infection ... EricsMedicalLectures/ #AKI
Approaches to Evaluating Kidney Disease in Patients with HIV Infection #Pathophys #Nephro #IM #HIV #CKD #AKI
Patients with HIV Infection ... #IM #HIV #CKD #AKI
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... Post-infectious ... • Toxins • Infection ... Koratala @NephroP #AKI
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... AIN: Medication, Infection ... Medicine @SCVMCMed #AKI
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... Kidney Injury (AKI ... allopurinol, PPI) • Infections ... Urolithiasis #AKI
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Kidney Injury ( AKI ... Inflammatory disease • Infection
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... When considering infections ... C. canimorsus infection ... Capnocytophaga infection ... Indiana University Infectious
Procalcitonin Limitations - Situations where PCT can be misinterpreted:
- Single value testing
- AKI/CKD
- Pancreatitis
- Cancers/Neoplasms
- Trauma
-
value testing - AKI ... Burns - Localized infections
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
Toxicities: • AKI ... hypovolemia) • GU infections