10 results
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... release Diagnosis ... #deficiency #CHF ... #management #cardiology
Iron Deficiency in Heart Failure - Diagnosis and Treatment Algorithm
Diagnosis: Ferritin <100 ng/mL (absolute ID) OR
Iron Deficiency ... Heart Failure - Diagnosis ... Ferritin <100 ng/mL ... Ferritin 100-299 ng/mL ... #management #algorithm
Iron Deficiency in Congestive Heart Failure (CHF)

Iron deficiency (ID) in heart failure is a common comorbidity
Iron Deficiency ... deficiency (ID) ... Exercise capacity Diagnosis ... Ferritin < 100 ng/mL ... #pharmacology #pathophysiology
A practical guide to starting levothyroxine therapy
Calculate full replacement dose: 1.6 mcg/kg/day
Young, otherwise healthy patient:
 •
of therapy • Start ... at 25-50 mcg/day ... proximity to PO iron ... initiation #starting #management ... #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-Hydroxylase Deficiency ... maintains appropriate ion ... amount of enzyme deficiency ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Symptoms: • Salt ... Serum DHEAS Diagnosis ... Administer 250 mcg ... addisons #disease #endocrinology ... #diagnosis #signs
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... ) - Diagnosis and ... Management Vitamin ... can lead to iron ... #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... Cellular immune deficiency ... #management #treatment
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
and Management ... malignancy Pathophysiology ... levels to <1ng/mL ... #Management #Endocrinology ... #Treatment #Pathophysiology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
neutropenia, and iron ... transplantation • MCC ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... #Management #Infections