2937 results
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
/ULN ALT) / (Alk ... specificity to elevated ALP ... • AST/ALT > ALP ... GGT/5-NT: ↑ • ALP ... chemistry #diagnosis #differential
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... ) Elevation - Differential ... Diagnosis Algorithm ALP ... - Increased ALP ... #Elevation #Differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... augment synthesis of ALP ... disease - If ALP ... both are normal, ALP ... injury #hepatitis #differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... or AST > ALP): ... • Severe - ALT ... Cholestatic Pattern (ALP ... > ALT or AST):
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Nucleotidase • ALT ... obstruction • ALP ... bile ducts Differential
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
box indicates all ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... Liver #Enzymes #Differential
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
kidney, brain ALT ... for the liver ALP ... Transaminase, ALP ... / ULN ALT) / (ALP ... / ULN ALP)
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Algorithm Severe ALT ... • Pregnancy - AFLP ... HELLP Moderate ALT ... #LiverEnzymes #Differential
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Injury • AST/ALT ... elevation > Alk ... phos • ALT more ... • R value = (ALT ... Transaminitis #diagnosis #differential
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Findings: • ↑AST/ALT ... , ↑Tbili/Dbili/AP ... infiltration) Differential ... iMedEducation #AFLP