13 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... Findings: • ↑AST/ALT ... iMedEducation #AFLP ... #management #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology ... #diagnosis
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
, ESRD Pathophysiology ... : • Clinical Suspicion ... D/c all heparin ... non-heparin A/C if clinical ... #Hematology #HemeOnc
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
will vary with clinical ... Can also be dosed ... Can also be dosed ... #CriticalCare # ... diagnosis #management
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
Sepsis - Diagnosis ... Clinical construct ... likelihood of prolonged ICU ... #SIRS #criticalcare ... #icu
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
esp in work-up/management ... if indicated, also ... • Most will also ... Pearls #Checklist #diagnosis ... #workup #criticalcare
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... unless severe APLS ... organ dysfuxtion, ICU ... coagulopathy, RRT/IMV as ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... of emergency, ICU ... #management #treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... permeability Diagnosis ... (for secondary APS ... #management #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
transplantation CLINICAL ... the underlying pathophysiology ... specific therapy, the clinician ... intensive care unit (ICU ... #management #neurology