13 results
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Anticonvulsants as ... Stevens-Johnson Syndrome ... , asthenia • Neurologic ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... (for secondary APS ... #neurology #rheumatology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... calcification appears as ... • Metabolic syndrome ... Gout #Comparison #rheumatology ... #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
nephrocalcinosis • CPPD ... membrane into the CNS ... adult population: also ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as ... nervous system (CNS ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... Medium and large also ... signs #symptoms #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... culture used to diagnose ... Crowned Dens Syndrome ... Deposition #Disease #Rheumatology ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
affects the skin, neurologic ... , mucositis • Rash ... aneurysms can also ... chorioretinitis, CNS ... #Rheumatology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... Diagnosis: MRI ... The clinical syndrome ... reversible • HAND is also ... dementia #AIDS #Neurology
Rickettsialpox Eschar

40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis?
Rickettsialpox R akari classic
Diagnosis? ... endothelial cells as ... rickettsia) Dx: serology ... rakari #clinical #photo ... #skinrash #dermatology