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diagnosis clinical management pocus cardiology differential video physicalexam algorithm pharmacology radiology ultrasound neurology treatment msk pathophysiology echocardiogram pulmonary orthopedics criticalcare
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT ... /ULN ALT) / (Alk ... • AST/ALT > ALP ... > AST/ALT: typical ... Kidney, Brain • ALT
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
or AST > ALP): ... • Severe - ALT ... • Moderate - ALT ... Others • Mild - ALT ... > ALT or AST):
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
LFTs) Elevation AST ... kidney, brain ALT ... Alkaline Phosphatase, ALT ... ULN R Value = (ALT ... / ULN ALT) / (ALP
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Injury • AST ... /ALT elevation > ... Alk phos • ALT ... • R value = (ALT ... + ULN ALT) / (alkaline
Standardized Physical Abuse Guideline <6 months of age • Social work consult • Skeletal survey • Head
, ALT, lipase ... Abdominal CT if AST ... or ALT 80 • Troponin ... months of age if AST ... or ALT> 80, signs
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
to liver than ALT ... • ALT: Specific ... • AST/ALT > ALP ... : ↑ • ALT: ↑ ... kidney, brain • ALT
Features of Components of Liver Function Tests #Diagnosis #IM #GI #LFTs #Liver #Function #Tests #Locations #AlkPhos
Locations #AlkPhos #AST ... #ALT #Ddxof
Gestational Hypertension & Preeclampsia Gestational Hypertension (gHTN) • BP > 140/90 • Onset > 20 wks gestation
Thrombocytopenia • Elevated AST ... /ALT • Pulmonary ... Thrombocytopenia • Elevated AST ... /ALT • Hemolysis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Algorithm Severe ALT ... HELLP Moderate ALT ... • Others Mild ALT
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
aminotransferase (AST ... aminotransferase (ALT
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