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signs differential management ana antibodies antinuclear apml classification comparison differentiation diffuse hematology pathophysiology patterns pericarditis presentation sarcoidosis sclerosis ssc syndrome
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... systemic sclerosis/scleroderma ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
common • Imaging: CXR ... - pulmonary opacities ... >3 symptoms, or> ... #management #hematology ... #oncology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
Infarction and Pulmonary ... associated with rheumatologic ... #Pericarditis #Symptoms ... #Signs #Presentation ... comparison #Table #Diagnosis
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 Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
e.g. incidental CXR ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary ... skin (16-32%): lupus ... #Management #Signs
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
Systemic Sclerosis (Scleroderma ... ) - Pulmonary ... Crackles, Abnormal CXR ... pathophysiology #signs ... #symptoms #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
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