14 results
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
HFrEF: Guideline ... , ARB, or ARNI AND ... or ARB • ARNI ... American patients #hfref ... #medications #chf
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

 •
Ejection Fraction (HFrEF ... Stepwise Approach: ACE ... -2 Inhibitor → ARNI ... Heart #Failure #CHF ... #HFrEF #Guideline
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy
 • Beta-blocker
 • ACE,
Ejection Fraction (HFrEF ... Beta-blocker • ACE ... , ARB, ARNI • ... Heart #Failure #CHF ... #HFrEF #Guideline
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
@DharSaty #HFrEF ... AngiotensinReceptorNeprilysinInhibitor #ACEi ... angiotensinreceptorblockers #ARB #ARNI ... #PARADIGM-HF #EMPEROR-Reduced
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
development of HF ... ACEI indicates angiotensin-converting ... heart failure; HFpEF ... ejection fraction; HFrEF ... #CHF #Congestive
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
initiate them on ACEI ... maximally tolerated ACEI ... Entresto (replacing ACEI ... /ambcarerx #CHF ... #sCHF #HeartFailure
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
for SGLT2i in HF ... for SGLT2i in HF ... in HFrEF on GDMT ... outcomes in HFrEF ... SGLT2 #inhibitors #EBM
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Ejection Fraction (HFrEF ... *Chronic HFrEF may ... Pharmacology: • ACE ... Inhibitors and ARBs • ARNIs ... Jcortesizaguirr #HFrEF
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
Therapy (GDMT) in HFrEF ... Class I pillars of HFrEF ... kidney disease: ACEI ... , ARB, ARNI, BBs ... therapies" for HFrEF
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction

CONCLUSIONS:
Among patients with heart failure and a
Dapagliflozin #hfref ... #chf #visualabstract ... #ebm