15 results
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

 •
Ejection Fraction (HFrEF ... Approach: ACE, ARB, ARNI ... -2 Inhibitor → ARNI ... Heart #Failure #CHF ... #HFrEF #Guideline
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy
 • Beta-blocker
 • ACE,
Ejection Fraction (HFrEF ... • ACE, ARB, ARNI ... Heart #Failure #CHF ... #HFrEF #Guideline
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
HFrEF: Guideline ... ACEI, ARB, or ARNI ... ACEI or ARB • ARNI ... American patients #hfref ... #medications #chf
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
@DharSaty #HFrEF ... angiotensinreceptorblockers #ARB #ARNI ... #PARADIGM-HF #EMPEROR-Reduced
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
for SGLT2i in HF ... for SGLT2i in HF ... in HFrEF on GDMT ... outcomes in HFrEF ... SGLT2 #inhibitors #EBM
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Ejection Fraction (HFrEF ... *Chronic HFrEF may ... → no signs of CXR ... Inhibitors and ARBs • ARNIs ... Jcortesizaguirr #HFrEF
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction

CONCLUSIONS:
Among patients with heart failure and a
Dapagliflozin #hfref ... #chf #visualabstract ... #ebm
Lung POCUS for Diagnosis of CHF - Visual Abstract
What is the accuracy of combined Lung Ultrasound
for Diagnosis of CHF ... 20.9 - LR- 0.07 CXR ... lung #ultrasound #CHF ... POCUS #diagnosis #ebm
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
Spironolactone #HFpEF ... #dCHF #Cardiology ... #EBM #VisualAbstract
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
Consider BCx, CSF ... diagnosed with CXR ... Diagnosis #Peds #EM