11 results
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
Must Be On" • ACEI ... , ARB, or ARNI AND ... or ARB • ARNI ... #medications #chf ... #cardiology #GDMT
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
DharSaty #HFrEF #GDMT ... AngiotensinReceptorNeprilysinInhibitor #ACEi ... angiotensinreceptorblockers #ARB #ARNI ... #PARADIGM-HF #EMPEROR-Reduced
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

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Stepwise Approach: ACE ... , ARB, ARNI → Beta-Blocker ... -2 Inhibitor → ARNI ... Heart #Failure #CHF ... Guideline #management #GDMT
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy
 • Beta-blocker
 • ACE,
Beta-blocker • ACE ... , ARB, ARNI • ... Heart #Failure #CHF ... Guideline #management #GDMT
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
HFrEF) Treatment - GDMT ... Medical Therapy (GDMT ... GDMT is basically ... initiate them on ACEI ... /ambcarerx #CHF
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
development of HF ... ACEI indicates angiotensin-converting ... ejection fraction; GDMT ... medical therapy; HF ... #CHF #Congestive
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
for SGLT2i in HF ... for SGLT2i in HF ... in HFrEF on GDMT ... outcomes in HFrEF on GDMT ... SGLT2 #inhibitors #EBM
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
Medical Therapy (GDMT ... pillars of HFrEF GDMT ... kidney disease: ACEI ... , ARB, ARNI, BBs ... after core GDMT
Target Doses in Congestive Heart Failure
 • Beta Blockers: Bisoprolol, Carvedilol, Metoprolol succinate, ARNI, Sacubitril/valsartan
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Metoprolol succinate, ARNI ... Sacubitril/valsartan • ACEI ... #HeartFailure #CHF
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
81% for acute HF ... 5 pts w/ acute HF ... Pharmacology: • ACE ... Inhibitors and ARBs • ARNIs ... #pharmacology #sCHF