21 results
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
Must Be On" • ACEI ... , ARB, or ARNI AND ... Reducing: • ACEI ... or ARB • ARNI ... chf #cardiology #GDMT
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
DharSaty #HFrEF #GDMT ... AngiotensinReceptorNeprilysinInhibitor #ACEi ... angiotensinreceptorblockers #ARB #ARNI
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

 •
Stepwise Approach: ACE ... , ARB, ARNI → Beta-Blocker ... -2 Inhibitor → ARNI ... Guideline #management #GDMT
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy
 • Beta-blocker
 • ACE,
Beta-blocker • ACE ... , ARB, ARNI • ... Guideline #management #GDMT
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
Medical Therapy (GDMT ... pillars of HFrEF GDMT ... kidney disease: ACEI ... , ARB, ARNI, BBs ... after core GDMT
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
HFrEF) Treatment - GDMT ... Medical Therapy (GDMT ... GDMT is basically ... initiate them on ACEI ... maximally tolerated ACEI
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAID vs ACEI/ARB ... that NSAIDs and ACEI ... ACEI/ARB's are often ... ACEIARB #Effects #Nephrology
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
ACEI indicates angiotensin-converting ... ejection fraction; GDMT
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
: NSAIDS, CNI, ACEI ... diagnosis #algorithm #nephrology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
• Avoid ARB/ACE-I ... /ARNI/MRA • Avoid ... pregnancy, teratogenic GDMT ... meds (e.g., ACE