10 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Definition: Diffuse ... Cough, Dyspnea, Fever ... symptomatology Differential ... anti-CCP • CXR (diffuse ... #differential #
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... Characterized by diffuse ... Nikolsky sign, the differential ... and toxic shock syndrome ... #Differential
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
and Focal) Differential ... Diagnosis Algorithm ... planopilaris Pattern ... • Loose anagen syndrome ... #Diagnosis #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... lymphadenopathy more diffuse ... involvement, irregular pattern ... Classification #pathophysiology ... #algorithm
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
to Headaches - Differential ... Diagnosis Algorithm ... PHANTOMS): • Pattern ... papilledema • Horner syndrome ... and signs (e.g., fever
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC ... w differential ... hemorrhage (DAH) • Diffuse ... • IF staining patterns ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Coronary arteries - Fever ... Vasculitis: • Fevers ... Lab Tests: • CBC ... - (C-ANCA) pattern ... - (P-ANCA) pattern
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 • Lupus erythematosus
 • Lichen
Diffuse Hair Loss ... (Alopecia) - Differential ... Diagnosis Algorithm ... planopilaris Pattern ... • Loose anagen syndrome
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... pneumonitis • Diffuse ... enteropathy, and diffuse ... to: Arthritis, Fever
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis

EPIDEMIOLOGY:
PFAPA is the most common syndrome entailing
Periodic Fever, ... (FMF) PATHOPHYSIOLOGY ... DIFFERENTIAL DIAGNOSIS ... dominant inheritance pattern ... Serial CBC counts