59 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
) and Treatment ... hypocalcemia Treatment ... hydroxide • Hyperkalemia ... - Standard treatment ... diagnosis #management #oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
spontaneously (before any treatments ... malignancies Treatments ... 6L/day) • For hyperkalemia ... Lysis #Syndrome #TLS ... #oncology #management
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... Consider cause of hyperkalaemia ... recurrence #Hyperkalemia ... #management #algorithm ... #treatment
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
intracellular ions and ... hyperuricemia, #hyperkalemia ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
) - Management and ... Treatment Algorithm ... DLBCL #Management #Treatment ... #Algorithm #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... leukapheresis - TLS ... Lysis Syndrome: • Pathophysiology ... hydration - Hyperkalemia ... Lysis #Syndrome #TLS
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... Diagnosis Algorithm ... Thrombocytosis: cells lyse as ... Differential #Diagnosis #Algorithm ... potassium #high #pathophysiology
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Definition • Pathophysiology ... Expectation • Rx Algorithm ... • Relapse and ... Anemia #diagnosis #oncology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Syndrome - Workup and ... of the above Treatment ... of Clinical TLS ... MatthewHoMD #TLS ... diagnosis #management #oncology
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
) BRASH Treatment ... • Aggressive treatment ... of hyperkalemia ... epinephrine (↑HR and ... diagnosis #management #pathophysiology