7 results
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... infective endocarditis ... #Causes #differential ... #culture #negative ... #Endocarditis #
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
Endocarditis Algorithm ... vs Noninfective Causes ... #Algorithm #Infective ... #Noninfective #Causes ... #Differential #
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... but important causes ... #Infective #Endocarditis ... #diagnosis #differential
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Cryoglobulinemia, Endocarditis ... Pauci-immune mediated (Negative ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Coagulase-negative ... Septic Emboli Cause ... Marantic (NTBE) Differential ... Paradoxical emboli via ASD ... Treat underlying cause
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential ... aureus, Coagulase-negative ... Septic emboli cause ... Treat underlying cause ... #Differential #
Pyogenic liver abscess in children
Common bacterial causes in children:
 • S.aureus
 • Strep spp
 • Enteric
Common bacterial causes ... • Enteric gram negative ... artery (e.g., endocarditis ... in those with concurrent ... children #peds #differential