16 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Intestine - Other causes ... Intestine • Kidney ... Pregnancy - Renal ... #Algorithm #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
tubule of the kidney ... Most cases diagnosed ... deficiency • blood ... neuropathy • Renal ... : - Renal failure
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Syndrome (HRS) - Diagnostic ... haematuria, Normal renal ... ultrasound HRS-NAKI ... - No other cause ... - No other cause
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
such as retinal hemorrhages ... disturbance, or acute kidney ... eg, presence of renal ... : Renal artery stenosis ... Renal parenchymal
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
UA positive for blood ... HYPOTENSION → renal ... vasoconstriction → decreased renal ... perfusion → renal ... Cast formation: Renal
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... ; hemorrhage and ... of Peripheral blood ... the presence of renal ... #Workup #Hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
muscle, liver, and kidney ... deficiency of red blood ... 94 and 84% Renal ... : • Renal infarction ... meningitis • Cerebral hemorrhage
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... Bleeding (64%) • Renal ... Acral cyanosis • Hemorrhagic ... #Coagulation #diagnosis ... #management #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... tract, and often causes ... Large Vessel: Blood ... • Urinalysis (Renal ... #rheumatology #
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, DIC, hypoTN, renal ... Causes purpura & ... RBCs (stored at 4C ... #Transfusion #diagnosis ... #management #hematology