32 results
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Diagnosis Algorithm ... Transcellular Shift: • Alkalosis ... Losses Non-renal ... vomiting) • Low ... #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
- Differential Diagnosis ... Algorithm Volume ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Algorithm #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Extra-renal Losses ... Bartter syndrome, Gitelman ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
- Differential Diagnosis ... Algorithm Volume ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Algorithm #Nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... • Normal or low ... (renal potassium ... #Syndrome #diagnosis ... #nephrology #management
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... Pathophysiology #nephrology ... #diagnosis
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
suggests extra-renal ... - Metabolic Alkalosis ... Bartter syndrome, Gitelman ... #diagnosis #Algorithm ... differential #potassium #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic Alkalosis ... - Differential Diagnosis ... Algorithm GI Losses ... Hypomagnesemia • Barrter's/Gitelman's ... MetabolicAlkalosis #NonGap #Nephrology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Algorithm Acidosis ... Renal artery stenosis ... #Diagnosis #Causes ... #Workup #Nephrology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
- Differential Diagnosis ... Bartter syndrome and Gitelman ... with secondary, hypocalcemia ... #causes #nephrology ... #magnesium #low