6 results
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
, Gitelman syndrome ... poisoning Normal acid-base ... and potassium acid ... urine #Algorithm #nephrology ... #differential #diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... Hypokalemia Metabolic alkalosis ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Cystinuria - Amino acid ... Liddle syndrome ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... D-lactate (short bowel syndrome ... sedation, narcotics, CVA ... #Summary #Nephrology ... #Base #Gas #VBG
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
- Differential Diagnosis ... Glucose, Acute resp. alkalosis ... Denosumab, Estrogen based ... , CA Inh., Osmotic ... Workup #phosphate #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Metabolic alkalosis ... • Diagnosis of ... Bumetanide, Ethacrynic acid ... Excretion #Diuresis #Nephrology ... #Medications #Table