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Initial Clinical and Laboratory Data Base for Defining Major Syndromes in Nephrology

#Major #Syndromes #Nephrology #Diagnosis #Workup
Laboratory Data Base ... in Nephrology ... #Major #Syndromes ... #Nephrology #Diagnosis ... #Differential #Table
Effects of Strokes by Location - Anterior vs Posterior Localization

Anterior Circulation 
 - MCA 
 -
Artery #Strokes #Syndromes ... #CVA #Territory ... Localization #Effects #Neurology ... #Diagnosis #Table ... Review in Clinical Neurology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... Hypokalemia Metabolic alkalosis ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
- Differential Diagnosis ... Glucose, Acute resp. alkalosis ... Denosumab, Estrogen based ... , CA Inh., Osmotic ... Workup #phosphate #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
, Gitelman syndrome ... poisoning Normal acid-base ... in the proximal tubule ... urine #Algorithm #nephrology ... #differential #diagnosis
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
: Differential Diagnosis ... diuretics after renal tubule ... indicates a renal tubule ... #Differential #Diagnosis ... #Causes #nephrology
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
- Differential Diagnosis ... Acute Respiratory Alkalosis ... inhibitor, Estrogen based ... #Differential #Diagnosis ... #Algorithm #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
limb Gitelman syndrome ... Liddle syndrome ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... D-lactate (short bowel syndrome ... sedation, narcotics, CVA ... #Summary #Nephrology ... bloodgas #Acid #Base
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
Hypernatremia Classification ... hypernatremia - Cushing's syndrome ... #Features #Diagnosis ... #Comparison #Table ... #Nephrology