14 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... nephron → - ↑ K+ ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology ... #diagnosis
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... Chloride • Urine Ca ... krithicism #Gitelman ... Bartter #Algorithm #nephrology ... #hypokalemia #diagnosis
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... ↑ Aldosterone: Kidney ... Bartter syndrome, Gitelman ... differential #algorithm #diagnosis ... #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... differentiating kidney ... Bartter syndrome, Gitelman ... #diagnosis #Algorithm ... differential #potassium #nephrology
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... - Management Treatment ... In persistent hypokalemia ... Ramesh @SRameshMD #Gitelman ... #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... syndrome - Na-K- ... cotransporter, K ... ascending limb Gitelman ... #Nephrology #Diagnosis
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential Diagnosis ... measuring urinary K ... Bartter's syndrome, Gitelman's ... #differential #diagnosis ... algorithm #causes #nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Blood Work: - Hypokalemia ... Inappropriate renal K+ ... of echogenic kidneys ... #Workup #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... distal convoluted tubule ... Rhabdomyolysis Treatment ... #Syndrome #diagnosis ... #nephrology #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Calcium 2-3g IV Ca-gluconate ... definitive guide to diagnosis ... #Diagnosis #Management ... #nephrology #K