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differential causes gitelman management syndrome algorithm pathophysiology potassium rhabdomyolysis treatment workup acidosis alkalosis aniongap anticoagulation chloride citrate defects diuresis diuretics
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... Pathophysiology #nephrology ... #diagnosis
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... Pressure: - Metabolic ... Hippurate - Metabolic ... #diagnosis #Algorithm ... differential #potassium #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Kidney ... Cl- outside the kidneys ... in the proximal tubule ... urine #Algorithm #nephrology ... #differential #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects in Kidney ... Tubule Epithelial ... Inherited #Defects #Kidney ... #Nephrology #Diagnosis ... #Differential #Table
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Non-anion Gap Metabolic ... Chronic progressive kidney ... aniongap #NonGap #Metabolic ... #differential #diagnosis ... #causes #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Heat stroke - Metabolic ... nephrotoxicity to kidney ... per day until stable ... causes #treatment #nephrology
Gitelman Syndrome - Diagnosis and Workup Blood Work: - Hypokalemia - Hypomagnesemia - Metabolic Alkalosis - Elevated
Blood Work: - Hypokalemia ... Hypomagnesemia - Metabolic ... autosomal dominant kidney ... of echogenic kidneys ... #Workup #nephrology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
and Differential Diagnosis ... with previously stable ... disturbance, or acute kidney ... and metabolic alkalosis ... Neurologic disorders
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Elimination (see Table ... Calcium 2-3g IV Ca-gluconate ... #Diagnosis #Management ... Treatment #potassium #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
distal convoluted tubule ... hypomagnesemia • Metabolic ... Hypochloremic metabolic ... Gitelman #Syndrome #diagnosis ... #nephrology #management
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