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management gitelman oncology pathophysiology causes cell clinical differential emergencies encephalopathy half hematology hemeonc hypokalemia k oncologic one oneandahalf ophthalmology palsy
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... H+ secretion → Hypokalemia ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... and Workup: • ... No additional workup ... #Management #Treatment ... #Neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... - Compartment syndrome ... kidney tubular cells ... #Differential #Diagnosis ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... reabsorption) Workup ... Calcium 2-3g IV Ca-gluconate ... Drives K+ into cells ... #nephrology #K
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Blood transfusion, Hypercalcemia ... narrowing on MRA/CTA ... epilepticus Treatment ... #neurology
One and a Half Syndrome on Physical Exam This 28 year old patient presented to clinic with
One and a Half Syndrome ... Entering VA was ... An APD was noted ... the hospital, diagnosed ... ophthalmology #neurology
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 Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
apical membrane of cells ... distal convoluted tubule ... • Unexplained hypokalemia ... Rhabdomyolysis Treatment ... #diagnosis #nephrology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... high LDH, low Ca ... plasmapheresis Hypercalcemia ... Oncology #HemeOnc #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
creating a “soap bubble ... CRAB - no anemia, hypercalcemia ... + diff • CMP, Ca ... Bone marrow Treatment ... #Workup #Hematology
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