26 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Onset Alzheimer's (1% ... - Presenilin 1 ... and 2 gene mutations ... - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology
Wolff-Parkinson-White Syndrome

WPW is a congenital abnormality characterized by an abnormal accessory conduction pathway between the atria
Wolff-Parkinson-White Syndrome ... ventricle known as the bundle ... The definitive treatment ... is ablation. 1 ... (Delta wave) 2
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment ... Summary #causes #treatment
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
weakness in: 1. ... Ptosis, diplopia 2. ... EMG Findings: 1. ... - Peek sign ... 2.
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... Specific sarcoidosis syndromes ... symptoms) • Löfgren syndrome ... • Heerfordt syndrome ... Diagnosis #Management #Signs
Peripheral Edema - Differential Diagnosis Framework for Lower Extremity Edema

Edema occurs when any of the following
conditions exist: (1) ... hydrostatic pressure (2) ... type 1 (reflex ... Lower #Extremity #PhysicalExam ... #Pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1- ... 2 cases/100,000 ... Guillain-Barre Pathophysiology ... main variants: (1) ... demyelination features (2)
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Episode - Minimum 1 ... mood - Primary treatment ... Episode - Minimum 2 ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
• Prevalence: 1- ... associated with DM-1, ... Pathophysiology ... Treatment: • ... Diagnosis #Management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... common in APL (2- ... Triggers: ATRA treatment ... Pathophysiology ... symptoms, or> 1