12 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Bartter Syndrome ... loop of Henle Gitelman ... #Fanconi #Bartter ... Nephron #Defects #Pathophysiology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
secreting tumor, Primary ... thiazide diuretics, Bartter ... syndrome, Gitelman ... Diagnosis #Algorithm #causes ... potassium #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
starts by measuring urinary ... • Diuretics, Bartter's ... syndrome, Gitelman's ... syndromePrimary ... #nephrology #potassium
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... Diagnosis #Algorithm #Nephrology ... #Causes
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
wasting from other causes ... suggests extra-renal causes ... mEq/g suggests urinary ... Emesis, Diuretics, Bartter ... syndrome, Gitelman
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
High Al, Low R - Primary ... h - Diuretics, Bartter's ... syndrome, Gitelman's ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... distal convoluted tubule ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #pathophysiology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... > 20 meq/L • Primary ... actively working • Bartter ... furosemide-like lesion) • Gitelman ... #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis - Urinary ... diuretic use, Bartter ... syndrome, Gitelman ... syndrome, Hypomagnesemia ... the indicated causes
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... Diagnosis #Algorithm #Nephrology ... #Causes