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diagnosis differential algorithm gravis management ophthalmology abg acid acidbase alice anticonvulsants base bloodgas confabulation cord extraocular gas generalized interpretation localization
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... Oculomotor • Myasthenia ... Lambert-Eaton Myasthenic ... Syndrome • Botulism ... #Neurology #Differential
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Causes of Proximal ... Muscle Weakness ... or peripheral neurologic ... disease • Myasthenia ... #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
an autoimmune disorder ... Ocular- 50%: Ptosis ... crises”. ... bulbar weakness ... diagnosis #management #neurology
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Guillain-Barre syndrome ... , Myasthenia Gravis ... #diagnosis #neurology
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Generalized Weakness ... Polyneuropathy, ALS), NMJ disorder ... (Myasthenia, LEMS ... Differential #Diagnosis #causes ... #neurology
Alice in Wonderland Syndrome What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
in Wonderland Syndrome ... (Many causes!) ... • Epilepsy • Psychiatric ... disorders • Toxic ... #diagnosis #neurology
Localizing Extraocular Movement Disorders • CN Ill (Oculomotor) Nerve Palsy • CN IV (Trochlear) Nerve
Extraocular Movement Disorders ... One-and-a-half Syndrome ... Skew Deviation Casey ... ophthalmology #neurology ... differential #diagnosis #ocular
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... Postsynaptic: Myasthenia ... • Inflammatory disorders ... aminotransferases • Serology ... Differential #Diagnosis #neurology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
More likely to cause ... or respiratory weakness ... Symptomatic treatment Of ocular ... glucocorticoids - can cause ... diagnosis #management #neurology
Confabulation What? Honest Lie. No incoming sensory information + Filling of the blanks with different information
Disease, Anton's Syndrome ... Cortical Blindness, Psychiatric ... Disorders By Dr ... differential #diagnosis #causes ... #neurology
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