11 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Oculomotor • Myasthenia ... Lambert-Eaton Myasthenic ... Syndrome • Botulism ... #Neurology #Differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Ocular- 50%: Ptosis ... Limb- proximal weakness ... crises”. ... bulbar weakness ... diagnosis #management #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Guillain-Barre syndrome ... , Myasthenia Gravis ... #diagnosis #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
NMO) - Clinical Manifestations ... desaturation, Scotoma, Ocular ... involvement: Intractable nausea ... , Myasthenia gravis ... #diagnosis #neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
More likely to cause ... or respiratory weakness ... Symptomatic treatment Of ocular ... glucocorticoids - can cause ... diagnosis #management #neurology
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Myasthenia gravis ... Neurogenic Ptosis - Neurologic ... to ptosis and weakness ... • Myasthenia gravis ... #Ptosis #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... H1N1) Clinical Manifestations ... Miller Fisher Syndrome ... management #treatment #neurology
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Neurological Manifestations ... onset of limb weakness ... Reconstitution Inflammatory Syndrome ... neurological symptoms • Caused ... differential #TB #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... transplantation CLINICAL MANIFESTATIONS ... Guillain #Barre #Syndrome ... diagnosis #management #neurology
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
soles in 50% of cases ... - Ocular syphilis ... manifestations ... and nephrotic syndrome ... have positive serology