8 results
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... ATP-sensitive potassium ... cells, triggering insulin ... #Summary #DM2 # ... diabetes #endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... Medication Guide Classes ... in Type 1 Diabetes ... #Mellitus #DM2 ... #Medications #pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... • Increases insulin-mediated ... agent • Does not cause ... #Metformin #Pharmacology ... diabetes #endocrinology
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
the dose of an ACEi ... Continue ACEi or ... ml/min per 1.73 m2 ... evidence-based pharmacologic ... #KDIGO #eGFR #Insulin
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Poorly controlled DM ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin ... differential #diagnosis #causes
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... glucose-dependent insulin ... not definitively cause ... #Summary #DM2 # ... diabetes #endocrinology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Poorly controlled DM ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin ... differential #diagnosis #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Medications: K+, ACEi ... transfusions), ↓insulin ... (DM, DKA, octreotide ... only if no clear cause ... Management #Treatment #potassium